Work on that playlist. If you like music and it helps you to be focused make the perfect playlist, add those staple songs of yours that make you wanna dance or sing your heart out every time it pops from shuffle and add a couple of new songs too so you can add excitement and surprise to the playlist. Try to make your playlist a little up beat, it doesn't have to be electronic music but don't go all the way to good ol' Mozart.
Make a plan. Plan out the days you'll be able to squeeze in a run, plan the distance you wish to achieve (but always be flexible) and plan out the times you feel most comfortable in. If you make the time to squeeze in a run you'll never get the chance to just say no because you're packed with things to do.
Bring a running buddy. Ask around your friends who'd like to get healthier with you, I don't think all of them would prefer to stay fat and have the same activity level as a couch, there must be somebody; and if there's not, make a running buddy. Sure you've seen somebody from your neighborhood running around.
Go little by little. Don't overdo your first run, it will only make you wanna crawl back home and never come out, do until the point you think is your climax and then walk your way back. Increse little by little and never feel bad for a little mileage. And never ever compare your runs to other's.
The first one to two miles are always the worst. Just tell yourself to keep going because around mile 3 you'll never want to stop.
Sign up for a race if you need a little motivation. A simple 5k will do it!
Go out and run. Stop reading this blog, don't second guess it and tie your running shoes on. GO!